The ministry of Higher education and research entrusted to the national Centre of scientific research (CNRS) a mission on scientific integrity. Scientific fraud is varied: biased manufacturing or forgery of results, biased interpretation or selection of data, alteration of curves or images, plagiarism, theft of ideas, financial profit-sharing's ... The increasing pressure which practices on the researchers (among which the career and the credits depend strictly on the quantity of articles and on produced results) tend to multiply the fraudulent practices.